Recombinant Mouse Styx Protein, Myc/DDK-tagged

• Cat.No.: Styx-6214M
• Product Overview: Purified recombinant protein of mouse full-length serine/threonine/tyrosine interaction protein (Styx), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates. Plays a role in spermatogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 25.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Styx serine/threonine/tyrosine interaction protein [ Mus musculus (house mouse) ]
• Official Symbol: Styx
• Synonyms: STYX; serine/threonine/tyrosine interaction protein; serine/threonine/tyrosine-interacting protein; protein tyrosine phosphatase-like protein; phosphoserine/threonine/tyrosine interaction protein; protein tyrosine phosphatase-like unspliced c-terminal product and spliced c-terminal end STYX; hStyxb; 0610039A20Rik; MGC106795
• Gene ID: 56291
• mRNA Refseq: NM_019637
• Protein Refseq: NP_062611
• UniProt ID: Q60969