Recombinant Mouse TNFSF11, Fc-tagged
Cat.No. : | Tnfsf11-198M |
Product Overview : | Recombinant Mouse TNFSF11 encoding the extracellular domain of mouse TNFSF11 (Arg 72-Asp 316), fused with the Fc region of human IgG1 at the N-terminus, was expressed in Human Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Tnfsf11-198M |
Description : | RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. |
Source : | Human Cells |
MolecularMass : | The recombinant mouse TNFSF11/Fc is a disulfide-linked homodimer. The reduced monomer comprises 505 amino acids and has a calculated molecular mass of 56 kDa. The apparent molecular mass of the monomer is approximately 50 kDa in SDS-PAGE under reducing conditions. |
PredictedN terminal : | Glu |
Formulation : | Lyophilized from 0.2μm filtered solution of PBS, pH7.4. |
Purity : | >87 % as determined by SDSPAGE. |
Endotoxin : | <1.0 EU per μg of the protein as determined by the LAL method |
Storage : | Store it under sterile conditions at -70 oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | Tnfsf11 |
Gene Name : | Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Mus musculus ] |
Synonyms : | Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11; ODF; OPG; OPGL; RANKL; Ly109l; Trance; OPG ligand; osteoprotegerin ligand; osteoclast differentiation factor; receptor activator of NF-kappaB ligand; tumor necrosis factor-related activation-induced cytokine; Ly109l |
Gene ID : | 21943 |
mRNA Refseq : | NM_011613 |
Protein Refseq : | NP_035743 |
UniProt ID : | O35235 |
Chromosome Location : | 14 D3 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity; protein binding; receptor activity; tumor necrosis factor receptor binding |
Products Types
◆ Recombinant Protein | ||
TNFSF11-4498H | Recombinant Human TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF11-683M | Recombinant Mouse TNFSF11 Protein | +Inquiry |
TNFSF11-459H | Recombinant Human TNFSF11 Protein, His-tagged | +Inquiry |
TNFSF11-210C | Active Recombinant Cynomolgus TNFSF11 protein(Gly136-Asp317), hFc-tagged | +Inquiry |
TNFSF11-2024M | Recombinant Mouse TNFSF11 Protein | +Inquiry |
◆ Lysates | ||
TNFSF11-001CCL | Recombinant Cynomolgus TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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