Recombinant Mouse Tpp1 protein, His-tagged

• Cat.No.: Tpp1-20M
• Product Overview: Recombinant Mouse Tpp1(Gly198~Pro562) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a lysosomal serine protease that cleaves N-terminal tripeptides from protein substrates. The encoded preproprotein undergoes autocatalytic processing to generate a mature enzyme. Mice lacking the encoded protein exhibit a progressive neurodegeneration and a greatly shortened lifespan. At the cellular level, mice lacking the encoded protein exhibit accumulation of autofluorescent lipopigments. Mutations in the human ortholog of this gene cause classical late-infantile neuronal ceroid lipofuscinosis.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 43.2kDa
• Protein length: Gly198~Pro562
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Tpp1 tripeptidyl peptidase I [ Mus musculus ]
• Official Symbol: Tpp1
• Synonyms: TPP1; tripeptidyl peptidase I; tripeptidyl-peptidase 1; LPIC; TPP-1; tripeptidyl peptidase-I; tripeptidyl-peptidase I; tripeptidyl aminopeptidase; ceroid-lipofuscinosis, neuronal 2; lysosomal pepstatin-insensitive protease; Cln2; TPP-I
• Gene ID: 12751
• mRNA Refseq: NM_009906
• Protein Refseq: NP_034036
• UniProt ID: O89023