Recombinant Mouse Tpx2 Protein, Myc/DDK-tagged
Cat.No. : | Tpx2-6615M |
Product Overview : | Purified recombinant protein of mouse full-length TPX2, microtubule-associated (Tpx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha. At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 85.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tpx2 TPX2, microtubule-associated [ Mus musculus (house mouse) ] |
Official Symbol : | Tpx2 |
Synonyms : | TPX2; TPX2, microtubule-associated protein homolog (Xenopus laevis); targeting protein for Xklp2; DIL2; p100; REPP86; 2610005B21Rik |
Gene ID : | 72119 |
mRNA Refseq : | NM_001141978 |
Protein Refseq : | NP_001135450 |
UniProt ID : | A2APB8 |
Products Types
◆ Recombinant Protein | ||
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TPX2-7044H | Recombinant Human TPX2, His-tagged | +Inquiry |
TPX2-17278M | Recombinant Mouse TPX2 Protein | +Inquiry |
TPX2-6007C | Recombinant Chicken TPX2 | +Inquiry |
◆ Lysates | ||
TPX2-829HCL | Recombinant Human TPX2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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