Recombinant Mouse Traf1 Protein, Myc/DDK-tagged

• Cat.No.: Traf1-6616M
• Product Overview: Purified recombinant protein of mouse full-length TNF receptor-associated factor 1 (Traf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 45.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Traf1 TNF receptor-associated factor 1 [ Mus musculus (house mouse) ]
• Official Symbol: Traf1
• Synonyms: TRAF1; TNF receptor-associated factor 1; 4732496E14Rik
• Gene ID: 22029
• mRNA Refseq: NM_009421
• Protein Refseq: NP_033447
• UniProt ID: P39428