Recombinant Mouse Traf3 Protein, Myc/DDK-tagged
Cat.No. : | Traf3-6618M |
Product Overview : | Purified recombinant protein of mouse full-length TNF receptor-associated factor 3 (Traf3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 64.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Traf3 TNF receptor-associated factor 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Traf3 |
Synonyms : | TRAF3; TNF receptor-associated factor 3; TRAFAMN; CD40 receptor-associated factor 1; amn; LAP1; CAP-1; CRAF1; T-BAM; CD40bp; AI528849 |
Gene ID : | 22031 |
mRNA Refseq : | NM_011632 |
Protein Refseq : | NP_035762 |
UniProt ID : | Q60803 |
Products Types
◆ Recombinant Protein | ||
TRAF3-4611H | Recombinant Human TRAF3 protein | +Inquiry |
TRAF3-6510H | Recombinant Human TRAF3 Protein (Lys6-Lys351), N-His tagged | +Inquiry |
TRAF3-3386H | Recombinant Human TRAF3, GST-tagged | +Inquiry |
TRAF3-3384H | Recombinant Human TRAF3, GST-tagged | +Inquiry |
TRAF3-3617H | Recombinant Human TRAF3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
TRAF3-823HCL | Recombinant Human TRAF3 293 Cell Lysate | +Inquiry |
TRAF3-822HCL | Recombinant Human TRAF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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