Recombinant Mouse TSLP protein(Met1-Glu140), His-tagged

• Cat.No.: Tslp-468M
• Product Overview: Recombinant Mouse TSLP (Q9JIE6) (Met 1-Glu 140) was expressed in HEK293, with a C-terminal polyhistidine tag.

Specification

• Source: HEK293
• Species: Mouse
• Tag: C-His
• Protein length: Met1-Glu140
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The secreted recombinant mouse TSLP comprises 132 amino acids and has a calculated molecular mass of 15.4 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 22-27 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Tslp thymic stromal lymphopoietin [ Mus musculus ]
• Official Symbol: TSLP
• Synonyms: TSLP; thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin
• Gene ID: 53603
• mRNA Refseq: NM_021367
• Protein Refseq: NP_067342

Reviews

04/04/2019

The TSLP protein offered by the manufacturer excels in its quality and is an excellent match for my experimental requirements.

02/25/2019

Their team of experts is readily available to address any queries or concerns I may have regarding the TSLP protein.

11/22/2016

Their team of experts is readily available to address any concerns or queries I may have regarding the TSLP protein.

Q&As

Can WDR5 play a role in non-cancerous diseases?

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment?

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

Are there any clinical trials involving WDR5-targeted therapies?

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases?

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

How can WDR5 be used as a diagnostic marker for cancer?

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.