Recombinant Mouse Uchl3 Protein, Myc/DDK-tagged
Cat.No. : | Uchl3-6820M |
Product Overview : | Purified recombinant protein of mouse full-length ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (Uchl3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3'', and exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 26.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) [ Mus musculus (house mouse) ] |
Official Symbol : | Uchl3 |
Synonyms : | UCHL3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; UCH-L3; ubiquitin thiolesterase; ubiquitin thioesterase L3 |
Gene ID : | 50933 |
mRNA Refseq : | NM_016723 |
Protein Refseq : | NP_057932 |
UniProt ID : | Q9JKB1 |
Products Types
◆ Recombinant Protein | ||
Uchl3-609R | Recombinant Rat Uchl3 Protein, His-tagged | +Inquiry |
UCHL3-0361H | Recombinant Human UCHL3 Protein (E2-A230), His tagged | +Inquiry |
UCHL3-0362H | Recombinant Human UCHL3 Protein (E2-A230), Tag Free | +Inquiry |
UCHL3-2303H | Recombinant Human UCHL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UCHL3-4899R | Recombinant Rhesus Macaque UCHL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
UCHL3-534HCL | Recombinant Human UCHL3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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