Recombinant Mouse Uros Protein, Myc/DDK-tagged

• Cat.No.: Uros-6858M
• Product Overview: Purified recombinant protein of mouse full-length uroporphyrinogen III synthase (Uros), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is the fourth enzyme in the heme biosynthesis pathway. It converts hydroxymethylbilane to uroporphyrinogen III, a cyclic tetrapyrrole. This enzyme is defective in the autosomal recessive disorder congenital erythropoietic porphyria. Alternate promoter usage controls cell type-specific expression, including erythroid cell-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 28.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Uros uroporphyrinogen III synthase [ Mus musculus (house mouse) ]
• Official Symbol: Uros
• Synonyms: UROS; uroporphyrinogen III synthase; uroporphyrinogen-III synthase; UROIIIS; URO-synthase; uroporphyrinogen-III cosynthase; uroporphyrinogen-III cosynthetase; hydroxymethylbilane hydrolyase (cyclizing); Uros3; AI415298
• Gene ID: 22276
• mRNA Refseq: NM_009479
• Protein Refseq: NP_033505
• UniProt ID: P51163