Recombinant Mouse Usp37 Protein, Myc/DDK-tagged
Cat.No. : | Usp37-6876M |
Product Overview : | Purified recombinant protein of mouse full-length ubiquitin specific peptidase 37 (Usp37), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 110 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Usp37 ubiquitin specific peptidase 37 [ Mus musculus (house mouse) ] |
Official Symbol : | Usp37 |
Synonyms : | USP37; ubiquitin specific peptidase 37; ubiquitin carboxyl-terminal hydrolase 37; ubiquitin thioesterase 37; deubiquitinating enzyme 37; ubiquitin thiolesterase 37; ubiquitin specific protease 37; ubiquitin-specific-processing protease 37; 4932415L06Rik; C330008N13Rik |
Gene ID : | 319651 |
mRNA Refseq : | NM_176972 |
Protein Refseq : | NP_795946 |
UniProt ID : | Q8C0R0 |
Products Types
◆ Recombinant Protein | ||
USP37-0349H | Recombinant Human USP37 Protein (S2-L979), Tag Free | +Inquiry |
USP37-9962M | Recombinant Mouse USP37 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP37-0350H | Recombinant Human USP37 Protein (S2-L979), His tagged | +Inquiry |
USP37-2327H | Recombinant Human USP37 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP37-17925M | Recombinant Mouse USP37 Protein | +Inquiry |
◆ Lysates | ||
USP37-459HCL | Recombinant Human USP37 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket