Recombinant Mouse Vdr Protein, Myc/DDK-tagged

• Cat.No.: Vdr-6914M
• Product Overview: Purified recombinant protein of mouse full-length vitamin D (1,25-dihydroxyvitamin D3) receptor (Vdr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 47.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor [ Mus musculus (house mouse) ]
• Official Symbol: Vdr
• Synonyms: VDR; vitamin D receptor; vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; Nr1i1
• Gene ID: 22337
• mRNA Refseq: NM_009504
• Protein Refseq: NP_033530
• UniProt ID: P48281