Recombinant Mouse Whamm Protein, Myc/DDK-tagged
Cat.No. : | Whamm-7000M |
Product Overview : | Purified recombinant protein of Mouse WAS protein homolog associated with actin, golgi membranes and microtubules (Whamm), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Proposed to use coordinated actin-nucleating and microtubule-binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex. Required for RhoD-dependent actin reorganization such as in cell adhesion and cell migration. Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 89.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Whamm WAS protein homolog associated with actin, golgi membranes and microtubules [ Mus musculus (house mouse) ] |
Official Symbol : | Whamm |
Synonyms : | Whamm; WAS protein homolog associated with actin, golgi membranes and microtubules; Whdc1; BB081391; mKIAA1971; WASP homolog-associated protein with actin, membranes and microtubules; WAS protein homology region 2 domain containing 1; WAS protein homology region 2 domain-containing protein 1; WH2 domain-containing protein 1 |
Gene ID : | 434204 |
mRNA Refseq : | NM_001004185 |
Protein Refseq : | NP_001004185 |
UniProt ID : | Q571B6 |
Products Types
◆ Recombinant Protein | ||
WHAMM-358H | Recombinant Human WHAMM Protein, MYC/DDK-tagged | +Inquiry |
WHAMM-10175M | Recombinant Mouse WHAMM Protein, His (Fc)-Avi-tagged | +Inquiry |
WHAMM-18543M | Recombinant Mouse WHAMM Protein | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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