Recombinant Mouse Yap1 Protein, Myc/DDK-tagged

• Cat.No.: Yap1-7027M
• Product Overview: Purified recombinant protein of Mouse yes-associated protein 1 (Yap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 51.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Yap1 yes-associated protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Yap1
• Synonyms: YAP1; yes-associated protein 1; yorkie homolog; 65 kDa Yes-associated protein; yes-associated protein, 65 kDa; Yap; Yki; Yap65; Yorkie; AI325207
• Gene ID: 22601
• mRNA Refseq: NM_009534
• Protein Refseq: NP_033560
• UniProt ID: P46938