Recombinant Mouse Zcchc8 Protein, Myc/DDK-tagged

• Cat.No.: Zcchc8-7067M
• Product Overview: Purified recombinant protein of Mouse zinc finger, CCHC domain containing 8 (cDNA clone MGC:19353 IMAGE:4238634), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 50.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Zcchc8 zinc finger, CCHC domain containing 8 [ Mus musculus (house mouse) ]
• Official Symbol: Zcchc8
• Synonyms: Zcchc8; zinc finger, CCHC domain containing 8; 5730565F05Rik; zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8
• Gene ID: 70650
• mRNA Refseq: NM_027494
• Protein Refseq: NP_081770
• UniProt ID: Q9CYA6