Recombinant Mouse Zfand2b Protein, Myc/DDK-tagged

• Cat.No.: Zfand2b-7075M
• Product Overview: Purified recombinant protein of Mouse zinc finger, AN1 type domain 2B (Zfand2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 27.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Zfand2b zinc finger, AN1 type domain 2B [ Mus musculus (house mouse) ]
• Official Symbol: Zfand2b
• Synonyms: ZFAND2B; zinc finger, AN1 type domain 2B; AN1-type zinc finger protein 2B; AIRAP-like protein; arsenite-inducible RNA-associated protein-like protein; C81256; 1110060O18Rik
• Gene ID: 68818
• mRNA Refseq: NM_001159905
• Protein Refseq: NP_001153377
• UniProt ID: Q91X58