Recombinant Mouse Zfp207 Protein, Myc/DDK-tagged
Cat.No. : | Zfp207-7080M |
Product Overview : | Purified recombinant protein of Mouse zinc finger protein 207 (Zfp207), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3. According to another report, the stabilization is independent of the proteasome. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 49.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Zfp207 zinc finger protein 207 [ Mus musculus (house mouse) ] |
Official Symbol : | Zfp207 |
Synonyms : | Zfp207; zinc finger protein 207; Ze; Zep; BuGZ; Znf207; 8430401D15Rik; BUB3-interacting and GLEBS motif-containing protein ZNF207; 49 kDa zinc finger protein |
Gene ID : | 22680 |
mRNA Refseq : | NM_001130171 |
Protein Refseq : | NP_001123643 |
UniProt ID : | Q9JMD0 |
Products Types
◆ Recombinant Protein | ||
ZNF207-10403M | Recombinant Mouse ZNF207 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZNF207-5123R | Recombinant Rhesus Macaque ZNF207 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZFP207-18849M | Recombinant Mouse ZFP207 Protein | +Inquiry |
ZNF207-5310R | Recombinant Rhesus monkey ZNF207 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ZNF207-122HCL | Recombinant Human ZNF207 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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