Recombinant Pig S100A11 protein, His-tagged

• Cat.No.: S100A11-2581P
• Product Overview: Recombinant Pig S100A11 aa. (Met1~Lys99 (Accession # P31950)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Pig
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 12 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Met1~Lys99 (Accession # P31950)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.4.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: S100A11 S100 calcium binding protein A11 [ Sus scrofa (pig) ]
• Official Symbol: S100A11
• Synonyms: S100A11; S100 calcium binding protein A11; protein S100-A11; S100C protein; calgizzarin; protein S100-C
• Gene ID: 445534
• mRNA Refseq: NM_001004045.1
• Protein Refseq: NP_001004045.1
• UniProt ID: P31950

Reviews

03/09/2021

Quality product, delivered on time—perfect!

01/30/2019

Fantastic quality, hassle-free delivery!

10/16/2018

A+ for both product quality and excellent service!

Q&As

Can you elaborate on the role of S100A11 in cellular signaling pathways, particularly those involved in cancer progression and metastasis?

S100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.

How does S100A11 contribute to cellular differentiation, and are there specific target genes or pathways involved in this process?

S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.

How is S100A11 expression regulated, and what are the transcriptional and post-translational mechanisms influencing its activity?

S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.

In neurodegenerative diseases, is there evidence of S100A11 involvement, and what are the potential mechanisms linking this protein to neurological pathology?

Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.

What is S100A11, and what is its cellular localization and physiological role?

S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.