| Description : |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
| Source : |
HEK293 |
| Species : |
Rabbit |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
47.3 kDa |
| Protein Length : |
267 |
| AA Sequence : |
GLAAALGLALLLLGLLLGAEPRPDC VGDTYPGGDRCCLECQPGYGMVSRC NRSQDTICHPCEPGFYNEAVNYQAC KPCTQCNRRSGSEPQQECTHTRDTV CRCRPGTQPLNGYKHGVDCAPCPQG HFSEGNNRACRPWTNCTLAGKRTLQ PASSISDAVCEDRSSLATQPWETPS APYRPPTARTSTAWPRTAQGPSTPT LEASKGPQLAIVLSLGLGLGLLALL AALLALYLHQRAWRPPKLPGGGSFR TPIQEEQADAGSTMAKI |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
