Recombinant Rat Amelx, His-tagged
Cat.No. : | Amelx-3407R |
Product Overview : | Amelogenin, X isoform (Amelx) |
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Description : | may play a role in mineralization of tooth enamel matrix . |
Source : | E. Coli or Yeast |
Species : | Rat |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 195 |
Purity : | >90% |
Notes : | Small volumes of Amelx recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | Amelx amelogenin, X-linked [ Rattus norvegicus ] |
Official Symbol : | Amelx |
Synonyms : | AMELX; amelogenin, X-linked; amelogenin, X isoform; LRAP; amelogenin X chromosome; leucine-rich amelogenin peptide; Amel; |
Gene ID : | 29160 |
mRNA Refseq : | NM_019154 |
Protein Refseq : | NP_062027 |
Function : | cell surface binding; growth factor activity; hydroxyapatite binding; identical protein binding; identical protein binding; structural constituent of tooth enamel; structural constituent of tooth enamel; structural constituent of tooth enamel; |
Products Types
◆ Recombinant Protein | ||
AMELX-305R | Recombinant Rat AMELX Protein, His (Fc)-Avi-tagged | +Inquiry |
AMELX-015H | Recombinant Human AMELX Protein, (AFPn)-His-TEV-tagged | +Inquiry |
AMELX-141R | Recombinant Rhesus Macaque AMELX Protein, His (Fc)-Avi-tagged | +Inquiry |
AMELX-7078H | Recombinant Human AMELX, His&SUMO-tagged | +Inquiry |
AMELX-5982H | Recombinant Human AMELX protein, His&Myc-tagged | +Inquiry |
◆ Lysates | ||
AMELX-70HCL | Recombinant Human AMELX cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAMELX undergoes various post-translational modifications, including phosphorylation and glycosylation, which contribute to its proper folding, secretion, and enamel matrix assembly.
AMELX gene regulation during tooth development is orchestrated by a complex interplay of transcription factors, epigenetic modifications, and signaling pathways, ensuring precise spatiotemporal expression for enamel formation.
AMELX contributes to the mechanical properties of enamel, such as its hardness, resilience, and wear resistance, through its involvement in enamel crystal organization and interlocking.
Manipulating AMELX expression or activity holds potential for enamel regeneration strategies, such as promoting ameloblast differentiation from stem cells or developing biomimetic materials that mimic the composition and structure of natural enamel for tooth repair and restoration.
Mutations or deletions in the AMELX gene result in amelogenesis imperfecta, leading to enamel defects, such as hypoplasia or hypomineralization, and compromised tooth integrity.
AMELX interacts with other enamel matrix proteins, such as amelogenin and enamelin, as well as extracellular matrix components, facilitating enamel matrix assembly, organization, and mineralization.
Signaling pathways, including Wnt, BMP, and FGF signaling, regulate AMELX expression and function, coordinating ameloblast differentiation, enamel secretion, and mineralization processes.
AMELX is highly expressed in ameloblasts, the cells responsible for enamel formation, and its role involves the synthesis and secretion of enamel matrix proteins essential for enamel structure and hardness.
AMELX plays a critical role in enamel mineralization by participating in the nucleation and growth of hydroxyapatite crystals, influencing their size, orientation, and arrangement within the enamel matrix.
AMELX expression may change during tooth aging or in dental diseases, reflecting altered enamel turnover, enamel remineralization processes, or adaptive responses to pathological conditions.
Customer Reviews (3)
Write a reviewPrecise quantification of protein expression changes in disease states.
Reduced assay background noise for improved signal-to-noise ratio.
Wide range of available detection methods for versatility.
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