Recombinant Rat AOX1 Protein, His (Fc)-Avi-tagged

• Cat.No.: AOX1-350R
• Product Overview: Recombinant Rat AOX1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rat
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Aox1 aldehyde oxidase 1 [ Rattus norvegicus ]
• Official Symbol: AOX1
• Gene ID: 54349
• mRNA Refseq: NM_019363.3
• Protein Refseq: NP_062236.2
• UniProt ID: Q9Z0U5

Reviews

05/16/2020

Using AOX1 can reduce the error in the experiment.

05/02/2020

Preserving its stability under extreme conditions, such as at high or low temperatures, is very advantageous for us to conduct experiments.

02/28/2020

Catalytic activity is very strong, which can significantly improve the selectivity and yield of chemical reactions, and has high application value.

09/27/2019

After using this recombinant protein, the lower limit of Western blot detection is greatly reduced.

Q&As

What is the pharmacological action of AOX1 ?

AOX1 can play anti-inflammatory, antioxidant and immunomodulatory roles in the body, and can produce therapeutic effects on many diseases.

Does AOX1 have an anti-inflammatory advantage?

AOX1 can reduce the body's inflammatory response, reduce the risk of infection, etc., is an effective anti-inflammatory drug.

What quality control is required for AOX1 ?

The quality control of AOX1 includes process control in the production process, evaluation of product quality characteristics and physical and chemical properties.

In what basic research is AOX1 applied?

AOX1 is used in basic research, such as cardiovascular diseases, immune system diseases, diabetes and other related research.

How is the clinical trial of AOX1 progressing?

AOX1 has been carried out a number of clinical trials, in the treatment of different diseases have achieved good efficacy.

What is the mechanism of action of AOX1 in cardiovascular diseases?

Recombinant AOX1 protein can coordinate the metabolism of oxygen free radicals and trans-lipid peroxides in the body, thereby reducing the risk of cardiovascular disease.

Does the fermentation process of AOX1 need to be optimized?

The AOX1 fermentation process needs to be optimized for mass transfer, metabolism and expression to improve yield and quality.

What are the advantages of AOX1 in the field of new drug development?

AOX1 has the advantages of high safety and stable effect in the research and development of new drugs.

What are the structural characteristics of AOX1 ?

The AOX1 has a molecular weight of about 38kDa and is characterized by a cofactor FAD, which shows monoglycine dehydrogenase activity in this linked molecule.

What are the storage conditions of AOX1 ?

AOX1 can be stably preserved at 4 degrees of refrigeration, and long-term storage needs to be stored at an ultra-low temperature environment of -80 degrees.

Is there any relationship between AOX1 and lupus erythematosus?

AOX1 is an immunomodulatory protein that can produce therapeutic effects on autoimmune diseases such as lupus erythematosus.

What are the indications for AOX1 ?

AOX1 can be used in the treatment of cardiovascular diseases, lupus erythematosus, autoimmune diseases and other diseases.

Is the therapeutic effect of AOX1 durable?

The therapeutic effect of AOX1 has a certain persistence, and the treatment regimen can be adjusted according to the patient's condition.

Which clinical application prospect of AOX1 ?

As a biomedical product, AOX1 has broad clinical application prospects in cardiovascular diseases, immune system diseases, metabolic diseases and other fields.

What is the dosage and use method of AOX1 ?

The dosage and use method of AOX1 need to be guided by the doctor according to the specific disease and patient situation.

What is the action mechanism of AOX1 in the treatment of diabetes?

AOX1 can help reduce blood sugar, improve insulin resistance, etc., so as to have a therapeutic effect on diabetes.

Does the production process of AOX1 ?

The production process of AOX1 includes gene cloning, fermentation, purification and other steps. Generally, E. coli expression system and mammalian cell expression system are used.

What is the significance of AOX1 spectral analysis?

AOX1 spectral analysis can help researchers study protein structure and properties, explore its mechanism of action in biological and medical research, and provide an important reference for subsequent research.

How safe is AOX1 ?

As a biomedical product, AOX1 needs to be strictly evaluated for safety in clinical application to ensure its safety.

How to purify AOX1 ?

AOX1 is often purified by affinity chromatography, ion exchange chromatography, gel filtration and other methods.