Recombinant Rat ATP2B4 Protein, His-tagged

• Cat.No.: ATP2B4-865R
• Product Overview: Recombinant Rat ATP2B4 Protein(NP_001005871)(Pro1018~Val1203), fused to N-terminal His tag, was expressed in E.coli.

Specification

• Source: E. coli
• Species: Rat
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Protein length: Pro1018~Val1203
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 [ Rattus norvegicus ]
• Official Symbol: ATP2B4
• Synonyms: ATP2B4; ATPase, Ca++ transporting, plasma membrane 4; plasma membrane calcium-transporting ATPase 4; plasma membrane calcium pump; plasma membrane Ca2+-ATPases 4; plasma membrane calcium ATPase; PMCA4
• Gene ID: 29600
• mRNA Refseq: NM_001005871
• Protein Refseq: NP_001005871
• UniProt ID: Q64542

Reviews

06/10/2021

Because it is not easy to be contaminated, it is stored again.

10/13/2020

The protein's activity is truly remarkable, able to catalyze reactions even under extreme conditions.

05/14/2020

ATP2B4's stability is truly remarkable, able to maintain its activity even under extreme conditions.

Q&As

Are mutations in ATP2B4 associated with rare genetic diseases?

ATP2B4 gene mutation may be related to some hereditary diseases such as acoustic neuroma and lung cancer.

What is the biological function of ATP2B4?

This is a calcium transporter, which is mainly responsible for transporting intracellular calcium to the outside of the cell, thereby maintaining the intracellular and extracellular calcium balance.

How does the protein structure and function of ATP2B4 differ from other atpase B family members?

There are several differences in protein structure and function between ATP2B4 and other atpase B family members, mainly depending on how they are expressed and regulated in different tissues and cells.

What are the pathways of ATP2B4 protein production?

The production pathway of ATP2B4 protein mainly includes multiple biological processes such as gene transcription, RNA splicing, protein translation and subsequent modification.

What diseases are associated with ATP2B4 expression?

The expression of ATP2B4 may be related to the occurrence and development of diabetes, obesity, cardiovascular disease, liver disease and other diseases.

Is ATP2B4 associated with cardiovascular disease?

The relationship between ATP2B4 and cardiovascular disease may be achieved through several mechanisms such as regulating cardiomyocyte contraction and vascular smooth muscle cell contraction.