Recombinant Rat Chrna1 Protein, His-tagged

• Cat.No.: Chrna1-778R
• Product Overview: Recombinant Rat Chrna1 Protein (Ser21-Phe245) with His tag was expressed in E. coli.

Specification

• Description: Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 1A and congenital myasthenic syndrome 1B. Orthologous to human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit).
• Source: E. coli
• Species: Rat
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.9 kDa; Accurate Molecular Mass: 30 kDa
• Protein length: Ser21-Phe245
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Gene Information

• Gene Name: Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) [ Rattus norvegicus ]
• Official Symbol: Chrna1
• Synonyms: CHRNA1; cholinergic receptor, nicotinic, alpha 1 (muscle); acetylcholine receptor subunit alpha; cholinergic receptor nicotinic alpha polypeptide 1; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
• Gene ID: 79557
• mRNA Refseq: NM_024485
• Protein Refseq: NP_077811
• UniProt ID: P25108