Recombinant Rat Cx3cl1 Chemokine (C-X3-C Motif) Ligand 1
Cat.No. : | Cx3cl1-128R |
- Specification
- Gene Information
- Related Products
Cat. No. : | Cx3cl1-128R |
Description : | Fractalkine (FKN) is a transmembrane mucin-chemokine hybrid molecule expressed on activated endothelium that mediates attachment and firm adhesion of T cells, monocytes and NK cells. FKN plays an important proinflammatory role in rheumatoid arthritis (RA) pathogenesis as characterized by induction of synovial angiogenesis, chemotaxis, activation of monocytes and T cells as well as the stimulation of proliferation and synthesis of matrix degrading enzymes (matrix metalloproteinases, MMP) in synovial fibroblasts. Fractalkine thus may represent a novel target molecule for therapeutic intervention in RA. FKN is also an essential biomarker for predicting the prognosis of patients with colorectal cancer (CRC). |
Molecular Weight : | The predicted molecular weight of Recombinant Rat Fractalkine is Mr 33 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa. |
Source : | Sf 21 Insect Cells. |
State Of Matter : | Lyophilized. |
Purity : | >97% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Cx3cl1 chemokine (C-X3-C motif) ligand 1 [ Rattus norvegicus ] |
Synonyms : | Cx3cl1; chemokine (C-X3-C motif) ligand 1; Cx3c; Scyd1; fractalkine; small inducible cytokine subfamily D, 1; small inducible cytokine subfamily D 1 |
Gene ID : | 89808 |
mRNA Refseq : | NM_134455 |
Protein Refseq : | NP_604450 |
UniProt ID : | O55145 |
Chromosome Location : | 19p12 |
Pathway : | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Function : | chemokine activity |
Products Types
◆ Recombinant Protein | ||
Cx3cl1-2385M | Active Recombinant Mouse Cx3cl1 Protein | +Inquiry |
Cx3cl1-880R | Recombinant Rat Cx3cl1 Protein, His-tagged | +Inquiry |
CX3CL1-878H | Recombinant Human CX3CL1 Protein, His-tagged | +Inquiry |
CX3CL1-1342R | Recombinant Rat CX3CL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cx3cl1-879M | Recombinant Mouse Cx3cl1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CX3CL1-840CCL | Recombinant Canine CX3CL1 cell lysate | +Inquiry |
CX3CL1-3019HCL | Recombinant Human CX3CL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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