Recombinant Rat Erbb2 Protein (Ala67-Val323), C-His tagged

• Cat.No.: Erbb2-6839R
• Product Overview: Recombinant rat Erbb2 (Ala67-Val323) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Description: Enables Hsp90 protein binding activity; protein tyrosine kinase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including animal organ development; nervous system development; and positive regulation of intracellular signal transduction. Located in several cellular components, including basolateral plasma membrane; lateral loop; and microvillus. Biomarker of congestive heart failure and median neuropathy. Human ortholog (s) of this gene implicated in carcinoma (multiple); dilated cardiomyopathy; high grade glioma; reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human ERBB2 (erb-b2 receptor tyrosine kinase 2).
• Source: Mammalian cells
• Species: Rat
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 127.27 kDa
• Protein Length: Ala67-Val323
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Erbb2 erb-b2 receptor tyrosine kinase 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Erbb2
• Synonyms: Erbb2; erb-b2 receptor tyrosine kinase 2; neu; HER2/neu; receptor tyrosine-protein kinase erbB-2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); C-erbB-2; NEU proto-oncogene; epidermal growth factor receptor-related protein; p185erbB2; p185neu; proto-oncogene NEU; proto-oncogene c-ErbB-2; receptor tyrosine-protein kinase erbB-2-like; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
• Gene ID: 24337
• mRNA Refseq: NM_017003
• Protein Refseq: NP_058699
• UniProt ID: P06494