Recombinant Rat Fgf2 Protein, His-tagged

• Cat.No.: Fgf2-1489R
• Product Overview: Recombinant Rat Fgf2 Protein (Pro10-Ser154) with N-His tag was expressed in E. coli.

Specification

• Description: Enables fibroblast growth factor receptor binding activity. Involved in several processes, including angiogenesis involved in coronary vascular morphogenesis; paracrine signaling; and positive regulation of cell population proliferation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in cytoplasm; extracellular space; and nucleus. Used to study pulmonary hypertension. Biomarker of bladder disease; decubitus ulcer; diabetic retinopathy; hypertension; and retinal vein occlusion. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2).
• Source: E. coli
• Species: Rat
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 20.0 kDa
  Accurate Molecular Mass: 20/23 kDa
• Protein length: Pro10-Ser154
• Purity: > 95%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Fgf2 fibroblast growth factor 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Fgf2
• Synonyms: FGF2; fibroblast growth factor 2; HBGF-2; basic fibroblast growth factor; heparin-binding growth factor 2; bFGF; Fgf-2
• Gene ID: 54250
• mRNA Refseq: NM_019305
• Protein Refseq: NP_062178
• UniProt ID: P13109