Active Recombinant Rat Ncr3 protein, His-tagged

• Cat.No.: Ncr3-1158R
• Product Overview: Recombinant Rat Ncr3 protein(CAD23066.1)(Met1-Ser147), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Rat
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: 1.Measured by its binding ability in a functional ELISA. 2.Immobilized rat NCR3-His at 10μg/mL (100μL/well) can bind rat B7-H6-Fc, the EC50 of rat B7-H6 -Fc is 1-20ng/mL.
• Molecular Mass: The recombinant rat Ncr3 consists 140 amino acids and predicts a molecular mass of 15.2 kDa.
• Protein Length: Met1-Ser147
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Ncr3 natural cytotoxicity triggering receptor 3 [ Rattus norvegicus ]
• Official Symbol: Ncr3
• Synonyms: NCR3; natural cytotoxicity triggering receptor 3; NK-p30; NK receptor 1c7; natural killer cell p30-related protein; 1C7; Nkp30
• Gene ID: 294251
• mRNA Refseq: NM_181822
• Protein Refseq: NP_861543

Reviews

02/01/2022

Choosing the NCR3 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.

12/16/2020

The manufacturer's commitment to customer satisfaction is unmatched.

01/13/2016

The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.

Q&As

Can NCR3 be used for personalized medicine?

The study of NCR3 expression and genetic variations may help tailor treatments for individuals with certain diseases, making it a potential component of personalized medicine.

How is NCR3 protein linked to inflammatory bowel disease (IBD)?

NCR3 is implicated in the pathogenesis of IBD, and drugs targeting this protein may offer new therapeutic options for patients with IBD.

How does NCR3 relate to autoimmune diseases?

NCR3 dysfunction has been associated with autoimmune diseases, and understanding its role may lead to new therapies.

Are there any challenges associated with NCR3-based therapies?

Challenges include potential side effects, limited understanding of NCR3 in some diseases, and the need for further clinical validation.

Are there any clinical trials involving NCR3 protein?

Yes, clinical trials are exploring NCR3-based immunotherapies for various cancers and infectious diseases.