Recombinant Rat Nppb Protein, His-tagged
Cat.No. : | Nppb-1851R |
Product Overview : | Recombinant Rat Nppb Protein (His27-Ser77) with N-His tag was expressed in E. coli. |
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Description : | Enables hormone activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of cell population proliferation; and positive regulation of cGMP-mediated signaling. Located in several cellular components, including extracellular space; perinuclear region of cytoplasm; and transport vesicle. Used to study hypertension; hypertensive heart disease; myocardial infarction; polycystic kidney disease; and proteinuria. Biomarker of several diseases, including artery disease (multiple); heart disease (multiple); hyperhomocysteinemia; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in atherosclerosis; hypertension; myocardial infarction; obesity; and systolic heart failure. Orthologous to human NPPB (natriuretic peptide B). |
Source : | E. coli |
Species : | Rat |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 9.5 kDa Accurate Molecular Mass: 12 kDa |
Protein length : | His27-Ser77 |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Nppb natriuretic peptide B [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Nppb |
Synonyms : | Nppb; natriuretic peptide B; BNP; Bnf; natriuretic peptides B; Brain natriuretic factor; brain natriuretic factor prohormone; brain natriuretic peptide; gamma-brain natriuretic peptide; iso-ANP; natriuretic peptide precursor B; natriuretic peptide precursor type B; preproBNP; proBNP |
Gene ID : | 25105 |
mRNA Refseq : | NM_031545 |
Protein Refseq : | NP_113733 |
UniProt ID : | P13205 |
Products Types
◆ Recombinant Protein | ||
NPPB-1409H | Recombinant Human NPPB Protein, His-tagged | +Inquiry |
NPPB-6042H | Recombinant Human NPPB Protein, GST-tagged | +Inquiry |
Nppb-390R | Recombinant Rat Nppb Protein, His&SUMO-tagged | +Inquiry |
NPPB-3706R | Recombinant Rat NPPB Protein, His (Fc)-Avi-tagged | +Inquiry |
NPPB-8050H | Synthetic Human Brain Natriuretic Peptide 32 | +Inquiry |
◆ Native Protein | ||
NPPB-8052R | Native Rat Brain Natriuretic Peptide-32 | +Inquiry |
Nppb-5459R | Native Rat Natriuretic Peptide B | +Inquiry |
◆ Lysates | ||
NPPB-3734HCL | Recombinant Human NPPB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionElevated NPPB levels are associated with fluid overload, providing valuable information for clinicians in managing patients with conditions like edema.
Yes, monitoring NPPB levels over time can help assess the effectiveness of treatments and interventions in managing cardiovascular conditions.
Normal ranges of NPPB may vary with age and gender. Understanding these variations is essential for accurate clinical interpretation.
While NPPB is a valuable marker, clinicians should consider factors like renal function and comorbidities that may affect its interpretation.
NPPB regulates blood pressure by promoting vasodilation and natriuresis. Understanding its levels can guide the management of hypertension.
Customer Reviews (3)
Write a reviewThey actively engage with researchers, comprehending their specific experimental needs, and offering tailored services accordingly.
This collaborative partnership facilitates a seamless and efficient research process, as the manufacturer aligns their support and services with my unique requirements.
The manufacturer's excellent technical support, commitment to innovation, and customer-centric approach further reinforce its suitability for my research.
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