Recombinant Rat Retn protein

• Cat.No.: Retn-1056R
• Product Overview: Recombinant Rat Retn protein was expressed in Escherichia coli.

Specification

• Description: May contribute to impaired glucose tolerance and inhibition of adipocyte differentiation.
• Source: E.coli
• Species: Rat
• Form: Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 0.02 % Tween-20.
• Molecular Mass: Approximately 20.2 kDa, a disulfide-linked homodimer consisting of two 95 amino acid polypeptide chains.
• Protein length: 95
• AA Sequence: MPSMSLCPMDEAISKKINQDFSSLL PAAMKNTVLHCWSVSSRGRLASCPE GTTVTSCSCGSGCGSWDVREDTMCH CQCGSIDWTAARCCTLRVGS
• Endotoxin: Less than 0.1 EU/μg of rRtResistin as determined by LAL method.
• Purity: >97% by SDS-PAGE and HPLC analysis.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.

Gene Information

• Gene Name: Retn
• Official Symbol: Retn
• Synonyms: RETN; resistin
• Gene ID: 246250
• mRNA Refseq: NM_144741
• Protein Refseq: NP_653342
• UniProt ID: Q8K4J7

Reviews

06/22/2020

Catalytic activity of RETN is excellent, no matter what the environment can maintain stable catalytic performance, its reliability is reliable.

05/27/2020

The quality of RETN they produce is guaranteed, and we can buy it with confidence.

05/22/2019

The stability of RETN is too strong to ignore, and it remains admirably stable after long storage.

Q&As

How does the expression level of RETN correlate with insulin resistance?

Expression level of RETN is associated with the development of insulin resistance. High levels of RETN can reduce insulin sensitivity, leading to decreased glycemic control, which promotes the development of insulin resistance.

What is the role of RETN in the treatment of diabetes and cardiovascular disease?

Studies have shown that regulating the expression level of RETN can influence the development and treatment effect of diabetes and cardiovascular disease. For example, certain drugs can improve insulin sensitivity and control blood sugar levels by inhibiting the expression level of RETN.

How can the expression level of RETN be used for the prediction and diagnosis of diabetes and cardiovascular disease?

Diabetes and cardiovascular disease can be predicted and diagnosed by measuring the expression level of RETN. For example, high levels of RETN may indicate a higher risk of disease and more severe disease conditions.

How to use mutation or abnormal expression of RETN for disease diagnosis and prognosis assessment?

Mutations and expression levels of the RETN gene can be detected to aid in diagnosing disease and assessing prognosis. For example, certain mutations may predict a higher risk and a worse prognosis.

What diseases are mutations or abnormal expression of RETN associated with?

Mutations or abnormal expression of RETN may be associated with a variety of diseases. For example, certain mutations can lead to abnormally elevated levels of their expression, increasing the risk of diabetes, cardiovascular disease, etc.

How does RETN relate to other biomarkers?

RETN has some association with other biomarkers. For example, in obesity and cardiovascular disease, the expression level of RETN can be used to assess the prognosis and therapeutic effect of the disease together with biomarkers such as adiponectin and leptin.