Recombinant Rat Serpina1 Protein, His-tagged

• Cat.No.: Serpina1-2052R
• Product Overview: Recombinant Rat Serpina1 Protein (Met1-Val257) with N-His tag was expressed in E. coli.

Specification

• Description: Enables serine-type endopeptidase inhibitor activity. Involved in several processes, including negative regulation of serine-type endopeptidase activity; response to estradiol; and response to methanol. Located in extracellular space. Used to study pulmonary hypertension. Biomarker of asthma; osteoarthritis; pancreatitis (multiple); primary hyperaldosteronism; and proteinuria. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; chronic obstructive pulmonary disease (multiple); human immunodeficiency virus infectious disease; inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1).
• Source: E. coli
• Species: Rat
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.3 kDa
  Accurate Molecular Mass: 44 kDa
• Protein length: Met1-Val257
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Serpina1 serpin family A member 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Serpina1
• Synonyms: Serpina1; serpin family A member 1; Pi; AAT; Spi1; alpha-1-antiproteinase; alpha-1-antitrypsin (protease inhibitor); alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine protease inhibitor alpha 1; serpin A1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
• Gene ID: 24648
• mRNA Refseq: NM_022519
• Protein Refseq: NP_071964
• UniProt ID: P17475