Recombinant Rat Sirt1 Protein, His-tagged
Cat.No. : | Sirt1-2058R |
Product Overview : | Recombinant Rat Sirt1 Protein (Met1-Tyr490) with N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Enables NAD-dependent histone deacetylase activity and protein kinase B binding activity. Involved in several processes, including cellular response to ketone; negative regulation of apoptotic process; and regulation of peptide hormone secretion. Located in cytosol; growth cone; and nucleus. Used to study middle cerebral artery infarction; obesity; osteoporosis; and type 2 diabetes mellitus. Biomarker of several diseases, including acute kidney failure; artery disease (multiple); impotence; non-alcoholic fatty liver disease; and obesity. Human ortholog(s) of this gene implicated in Huntington's disease and prostate cancer. Orthologous to human SIRT1 (sirtuin 1). |
Source : | E. coli |
Species : | Rat |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 58.5 kDa Accurate Molecular Mass: 66 kDa |
Protein length : | Met1-Tyr490 |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Sirt1 sirtuin 1 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Sirt1 |
Synonyms : | SIRT1; sirtuin 1; NAD-dependent deacetylase sirtuin-1; Sir2alpha; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; Sir2; |
Gene ID : | 309757 |
mRNA Refseq : | NM_001107627 |
Protein Refseq : | NP_001101097 |
Products Types
◆ Recombinant Protein | ||
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◆ Lysates | ||
SIRT1-595HCL | Recombinant Human SIRT1 lysate | +Inquiry |
◆ Assay kits | ||
Kit-2024 | SIRT1 Direct Fluorescent Screening Assay Kit | +Inquiry |
Kit-2156 | SIRT1 Inhibitor/Activator Screening Kit | +Inquiry |
Kit-2025 | SIRT1 FRET-Based Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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