Recombinant Rat SMARCA4 Protein, His-tagged

• Cat.No.: SMARCA4-15R
• Product Overview: Recombinant Rat SMARCA4 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: Enables chromatin binding activity. Involved in negative regulation of transcription, DNA-templated; nucleosome disassembly; and spermatid development. Located in nucleus. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid cancer. Orthologous to human SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Liquid. In 1xPBS (pH 7.4).
• Molecular Mass: ~110.2 kDa
• Protein length: 756-1347aa
• AA Sequence: MKIEEGKLVIWINGDKGYNGLAEVG KKFEKDTGIKVTVEHPDKLEEKFPQ VAATGDGPDIIFWAHDRFGGYAQSG LLAEITPDKAFQDKLYPFTWDAVRY NGKLIAYPIAVEALSLIYNKDLLPN PPKTWEEIPALDKELKAKGKSALMF NLQEPYFTWPLIAADGGYAFKYENG KYDIKDVGVDNAGAKAGLTFLVDLI KNKHMNADTDYSIAEAAFNKGETAM TINGPWAWSNIDTSKVNYGVTVLPT FKGQPSKPFVGVLSAGINAASPNKE LAKEFLENYLLTDEGLEAVNKDKPL GAVALKSYEEELAKDPRIAATMENA QKGEIMPNIPQMSAFWYAVRTAVIN AASGRQTVDEALKDAQTQYQIKGLE WLVSLYNNNLNGILADEMGLGKTIQ TIALITYLMEHKRINGPFLIIVPLS TLSNWAYEFDKWAPSVVKVSYKGSP AARRAFVPQLRSGKFNVLLTTYEYI IKDKHILAKIRWKYMIVDEGHRMKN HHCKLTQVLNTHYVAPRRLLLTGTP LQNKLPELWALLNFLLPTIFKSCST FEQWFNAPFAMTGEKVDLNEEETIL IIRRLHKVLRPFLLRRLKKEVEAQL PEKVEYVIKCDMSALQRVLYRHMQA KGVLLTDGSEKDKKGKGGTKTLMNT IMQLRKICNHPYMFQHIEESFSEHL GFTGGIVQGLDLYRASGKFELLDRI LPKLRATNHKVLLFCQMTSLMTIME DYFAYRGFKYLRLDGTTKAEDRGML LKTFNEPGSEYFIFLLSTRAGGLGL NLQSADTVIIFDSDWNPHQDLQAQD RAHRIGQQNEVRVLRLCTVNSVEEK ILAAAKYKLNVDQKVIQAGMFDQKS SSHERRAFLQAILEHEEQDEEEDEV PDDETVNQMIARHEEEFDLFMRMDL DRRREEARNPKRKPRLMEEDELPSW IIKDDAEVERLTCEEEEEKMFGRGS RHRKEVDYSHHHHHH
• Purity: >90%
• Storage: Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20 to -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.21 mg/ml
• Official Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Gene Information

• Gene Name: Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: SMARCA4
• Synonyms: brg-1
• Gene ID: 171379
• mRNA Refseq: NM_134368
• Protein Refseq: NP_599195
• UniProt ID: Q8K1P7