Recombinant Rat Tgfb1 Protein, His-SUMO-tagged

• Cat.No.: Tgfb1-1384R
• Product Overview: Recombinant Rat Tgfb1 Protein (30-278aa) was expressed in E. coli with N-terminal His-SUMO tag.

Specification

• Source: E. coli
• Species: Rat
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol.
• Molecular Mass: 44.5 kDa
• AA Sequence: LSTCKTIDMELVKRKRIEAIRGQIL SKLRLASPPSQGEVPPGPLPEAVLA LYNSTRDRVAGESADPEPEP
  EADYYAKEVTRVLMVDRNNAIYDKT KDITHSIYMFFNTSDIREAVPEPPL LSRAELRLQRFKSTVEQHVE
  LYQKYSNNSWRYLGNRLLTPTDTPE WLSFDVTGVVRQWLNQGDGIQGFRF SAHCSCDSKDNVLHVEINGI
  SPKRRGDLGTIHDMNRPFLLLMATP LERAQHLHSSRHRR
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.

Gene Information

• Gene Name: Tgfb1 transforming growth factor, beta 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Tgfb1
• Synonyms: Tgfb1; Tgfb
• Gene ID: 59086
• mRNA Refseq: NM_021578.2
• Protein Refseq: NP_067589.1
• UniProt ID: P17246

Reviews

11/16/2021

The impressive performance of the TGFB1 protein both in ELISA assays and protein electron microscopy structure analysis makes it a highly versatile and recommended choice for scientists across various disciplines.

03/01/2020

Its reliability and efficacy in generating high-quality data make it an indispensable tool in the quest for unraveling the mysteries of protein structure and function.

07/16/2018

The TGFB1 protein's excellent performance in ELISA ensures accurate and reproducible results, enhancing the reliability of experimental data.

Q&As

How is TGFB1 involved in bone remodeling?

TGFB1 stimulates the activity of cells involved in bone formation (osteoblasts) and plays a role in regulating bone resorption by influencing osteoclast function.

Are there any side effects associated with therapies targeting TGFB1?

Potential side effects of anti-TGFB1 therapies may include immune system suppression, gastrointestinal issues, and skin reactions.

Can TGFB1 be used as a biomarker for certain diseases?

TGFB1 levels have been studied as potential biomarkers for diseases like cancer and fibrosis, aiding in diagnosis and monitoring disease progression.

In what ways does TGFB1 influence wound healing?

TGFB1 plays a critical role in wound healing by stimulating the formation of new blood vessels, promoting the production of extracellular matrix, and aiding in the migration of cells to the wound site.

How does TGFB1 contribute to fibrosis?

TGFB1 can induce the production of excessive extracellular matrix proteins, leading to tissue scarring and fibrosis in organs such as the liver, lung, and kidneys.