Recombinant Rat TGFBR3 Protein

• Cat.No.: TGFBR3-6040R
• Product Overview: Recombinant Rat TGFBR3 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rat
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Tgfbr3 transforming growth factor, beta receptor III [ Rattus norvegicus ]
• Official Symbol: TGFBR3
• Gene ID: 29610
• mRNA Refseq: NM_017256.1
• Protein Refseq: NP_058952.1
• UniProt ID: P26342

Reviews

05/10/2022

Great product !

02/18/2020

Seamless delivery process—ordered, received, and ready for experiments.

08/31/2018

Timely delivery is key, and this product arrived on schedule.

Q&As

What are the implications of TGFBR3 mutations in the context of hereditary connective tissue disorders?

TGFBR3 mutations are associated with hereditary connective tissue disorders, impacting extracellular matrix homeostasis and contributing to conditions like Loeys-Dietz syndrome.

How does TGFBR3 influence embryonic development, and what are the consequences of its dysregulation during development?

TGFBR3 plays a role in embryonic development, and dysregulation may lead to developmental abnormalities due to disrupted TGF-beta signaling.

Can you explain the role of TGFBR3 in mediating interactions between cells and extracellular matrix components?

TGFBR3 facilitates cell-ECM interactions by modulating TGF-beta signaling, influencing processes like cell adhesion and migration.

How does TGFBR3 contribute to the modulation of TGF-beta signaling pathways?

TGFBR3 acts as a co-receptor, enhancing the binding of TGF-beta ligands to TGF-beta receptors, and modulates downstream signaling events.

What are the functional consequences of TGFBR3 mutations in the context of cardiovascular diseases?

TGFBR3 mutations are implicated in cardiovascular diseases, affecting TGF-beta-mediated processes in vascular smooth muscle cells and cardiac tissues.