Recombinant Rat Tnfsf11
Cat.No. : | Tnfsf11-2680R |
Product Overview : | Recombinant rat Tnfsf11 is a 19.4 kDa polypeptide comprising the TNF homologous region of RANKL (174 amino acid residues). It is expressed inE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Tnfsf11-2680R |
Description : | RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a molecule important in bone metabolism. This natural and necessary surface-bound molecule found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and psoriatic arthritis. |
Source : | E. coli. |
Purity : | Greater than 98% (determined by SDS-PAGE and HPLC analysis). |
MW : | 19.4 kDa. |
Endotoxin Level : | < 0.1 ng per μg of rHu APO-E4 (1EU/μg). |
Formulation : | Lyophilized from a sterile-filtered solution with no additives. |
Reconstitution : | Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity. |
Storage : | The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles. |
Gene Name : | Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Rattus norvegicus ] |
Synonyms : | Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11; ODF; OPGL; TNF-related activation-induced cytokine; TRANCE; osteoclast differentiation factor; osteoprotegerin ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor ligand superfamily member 11; RANKL |
Gene ID : | 117516 |
mRNA Refseq : | NM_057149 |
Protein Refseq : | NP_476490 |
UniProt ID : | Q9ESE2 |
Chromosome Location : | 15q11 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity; protein binding; tumor necrosis factor receptor binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
Tnfsf11-317M | Recombinant Active Mouse TNFSF11 Protein, His-tagged(C-ter) | +Inquiry |
TNFSF11-683M | Recombinant Mouse TNFSF11 Protein | +Inquiry |
Tnfsf11-6551M | Active Recombinant Mouse Tnfsf11 Protein | +Inquiry |
TNFSF11-255M | Active Recombinant Mouse TNFSF11 Protein | +Inquiry |
TNFSF11-459H | Recombinant Human TNFSF11 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-001CCL | Recombinant Cynomolgus TNFSF11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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