Recombinant Rhesus Macaque ACO2 Protein Pre-coupled Magnetic Beads
Cat.No. : | ACO2-38R-B |
Product Overview : | The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations. |
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Source : | HEK293 |
Species : | Rhesus Macaque |
Form : | Solution |
Particle size : | ~2 μm |
Beads Surface : | Hydrophilic |
Capacity : | > 200 pmol rabbit IgG/ mg beads |
Applications : | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. |
Storage : | 2-8℃. Do not to freeze thaw the Beads |
Concentration : | 10mg beads/mL |
Storage Buffer : | PBS buffer |
Gene Name : | ACO2 aconitase 2, mitochondrial [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | ACO2 |
Synonyms : | ACO2; aconitate hydratase, mitochondrial; |
Gene ID : | 707441 |
mRNA Refseq : | NM_001261164 |
Protein Refseq : | NP_001248093 |
UniProt ID : | F7BKH7 |
Products Types
◆ Recombinant Protein | ||
ACO2-914H | Recombinant Human ACO2 Protein, MYC/DDK-tagged | +Inquiry |
ACO2-38R | Recombinant Rhesus Macaque ACO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACO2-258H | Recombinant Human ACO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Aco2-513M | Recombinant Mouse Aco2 Protein, MYC/DDK-tagged | +Inquiry |
ACO2-111R | Recombinant Rat ACO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACO2-440MCL | Recombinant Mouse ACO2 cell lysate | +Inquiry |
ACO2-498HCL | Recombinant Human ACO2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionACO2 is involved in the TCA cycle, which is a critical process for energy production in cells. Specifically, it catalyzes the conversion of citrate to isocitrate, which is a crucial step in the cycle.
Yes, mutations in the ACO2 gene have been associated with several disorders, including infantile cerebellar-retinal degeneration and mitochondrial encephalopathy. These conditions are characterized by a range of symptoms, including neurological and developmental abnormalities.
ACO2 is a potential target for cancer treatment, as it is overexpressed in several types of cancer cells. However, the development of drugs that target ACO2 is still in the early stages of research.
ACO1 and ACO2 are two isoforms of aconitate hydratase, which catalyze the same reaction in the TCA cycle. However, ACO2 is primarily located in the mitochondria of cells, while ACO1 is located in the cytoplasm.
Unlike ACO1, ACO2 is not involved in iron metabolism. Its role is primarily in energy production through the TCA cycle.
ACO2 deficiency has been associated with several disorders, including infantile cerebellar-retinal degeneration and mitochondrial encephalopathy. These conditions are characterized by various neurological and developmental abnormalities.
ACO2 is a homodimeric enzyme composed of two identical subunits. Each subunit contains a catalytic domain and a regulatory domain, which work together to catalyze the isomerization of citrate to isocitrate.
ACO2 activity can be measured in the laboratory using a variety of techniques, including spectrophotometric assays and enzymatic activity assays. These assays typically involve measuring the rate of citrate isomerization to isocitrate in the presence of ACO2 and other necessary cofactors.
ACO2 activity is regulated by a variety of factors, including substrate availability, pH, and post-translational modifications such as phosphorylation. Additionally, ACO2 activity can be modulated by other enzymes and metabolic pathways in the cell.
While ACO2 is primarily known for its role in energy production, recent research suggests that it may also play a role in other cellular processes. For example, studies have shown that ACO2 may be involved in regulating the immune response and cellular metabolism.
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