Recombinant Rhesus Macaque AFTPH Protein, His (Fc)-Avi-tagged

• Cat.No.: AFTPH-93R
• Product Overview: Recombinant Rhesus Macaque AFTPH with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rhesus Macaque
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: AFTPH aftiphilin [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: AFTPH
• Synonyms: AFTPH; aftiphilin
• Gene ID: 696100
• mRNA Refseq: NM_001257727
• Protein Refseq: NP_001244656
• UniProt ID: F7H927

Reviews

08/30/2022

Mapping protein-protein interactions in extracellular matrix assembly for tissue integrity.

06/09/2021

Studying protein-protein interactions in receptor signaling for cellular communication.

03/23/2018

Probing protein-protein interactions in ion channel function for neuronal excitability.

Q&As

Are there disease-associated mutations in the AFTPH gene?

There is currently no known association between disease and mutations in the AFTPH gene.

How does AFTPH protein influence cellular morphology and cytoskeleton?

AFTPH protein participates in the remodeling of the cytoskeleton and dynamic regulation of the cell membrane, affecting cellular morphology.

Which molecules interact with AFTPH protein?

AFTPH protein interacts with multiple signaling proteins, cytoskeletal proteins, and transcription factors.

How does AFTPH protein contribute to cellular signal transduction networks and protein complexes?

AFTPH protein interacts with various signaling pathways and protein complexes, influencing cellular signal transduction and dynamics.

How does AFTPH protein regulate cellular functions through signaling pathways?

AFTPH protein regulates cellular functions by activating signaling pathways like PI3K/Akt and MAPK.

What is the subcellular localization and trafficking mechanism of AFTPH protein?

AFTPH protein is mainly localized in the cytoplasm and participates in trafficking processes involving the endoplasmic reticulum and Golgi apparatus.

How is the expression of AFTPH protein regulated?

The expression of AFTPH protein is regulated through transcriptional and post-transcriptional mechanisms.

What is the functional role of AFTPH protein?

AFTPH protein is involved in regulating various cellular processes, such as migration, adhesion, proliferation, and signaling.

What are the physiological roles of AFTPH protein in development, tissue homeostasis, or disease progression?

The precise physiological roles of AFTPH protein in embryonic development, tissue homeostasis, and tumor progression require further investigation.

Can manipulating AFTPH protein modulate specific cellular functions or signaling pathways?

Inhibiting the expression or activity of AFTPH protein can modulate processes like cell migration, proliferation, and tumor development.