Recombinant Rhesus Macaque CACYBP Protein Pre-coupled Magnetic Beads

• Cat.No.: CACYBP-434R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rhesus Macaque
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: CACYBP calcyclin binding protein [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CACYBP
• Synonyms: CACYBP; calcyclin-binding protein
• Gene ID: 709343
• mRNA Refseq: NM_001266661
• Protein Refseq: NP_001253590
• UniProt ID: H9FSZ4

Reviews

11/15/2021

I saw results within weeks.

04/19/2020

Impressed with the results.

07/06/2018

High-quality product.

Q&As

How does the phosphorylation of CACYBP influence its biochemical properties and cellular functions?

Phosphorylation of CACYBP can modulate its protein-protein interactions and stability. Phosphorylation events may affect its role in cell cycle regulation and ubiquitin-dependent protein degradation.

How does CACYBP's calcium-binding capability influence its conformational dynamics and interactions with calcium-dependent proteins?

CACYBP's calcium-binding domains undergo conformational changes upon calcium binding, which can affect its interactions with other proteins. It allows CACYBP to act as a calcium-dependent scaffold for various signaling complexes.

What are the biochemical mechanisms underlying the influence of CACYBP on cell cycle progression, including its interactions with Cyclins and CDKs?

CACYBP interacts with Cyclins and CDKs, forming complexes that regulate the phosphorylation of key cell cycle regulators. These interactions affect the progression through different phases of the cell cycle.

Can you explain the role of CACYBP in ubiquitin-dependent protein degradation and its connection to the proteasome system?

CACYBP functions as an adaptor protein in ubiquitin-dependent protein degradation by facilitating the transfer of ubiquitin moieties to target proteins. It forms complexes with E3 ubiquitin ligases and substrates, directing them to the proteasome for degradation.

Can you discuss the role of CACYBP in cellular responses to stress, including oxidative stress and DNA damage, and its molecular mechanisms in these contexts?

CACYBP participates in stress responses by modulating the stability and activity of proteins involved in stress pathways. For example, it can influence the stability of DNA repair proteins and oxidative stress response factors, contributing to cellular adaptation to stress conditions.