Recombinant Rhesus Macaque CNR1 Protein Pre-coupled Magnetic Beads

• Cat.No.: CNR1-772R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rhesus Macaque
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: CNR1 cannabinoid receptor 1 (brain) [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CNR1
• Synonyms: CNR1; cannabinoid receptor 1; CB-R; CB1; cannabinoid receptor CB-1
• Gene ID: 574142
• mRNA Refseq: NM_001032825
• Protein Refseq: NP_001027997
• UniProt ID: G7MPW5

Reviews

08/18/2022

DNA binding ability is strong, and it performs well in related experiments.

04/24/2022

The immunogenicity is very weak, does not cause an immune response, and has a high safety profile.

04/09/2022

CNR1 has a long shelf life and good stability, which is convenient for the continuity of subsequent experiments.

Q&As

What are the mechanisms of action of CNR1 receptor agonists and antagonists?

The protein receptor agonists can bind to receptors, activate receptors, and promote their signal transduction, resulting in physiological effects. CNR1 receptor antagonists, on the other hand, can bind to the receptor and prevent endocannabinoids from binding to the receptor, thereby inhibiting its signal transduction.

What are the types of CNR1 mutations?

There are many types of mutations in the CNR1 gene, including single nucleotide substitution, insertion, or deletion. These mutations may cause structural and functional changes in the CNR1 receptor, affecting its binding and signal transduction to endocannabinoids.

What role does the CNR1 receptor play in neuronal connections and neural circuits?

CNR1 receptors play an important role in neuronal connections and neural circuits. It is involved in the growth, differentiation, and synapse formation of neurons, as well as in the regulation of neural circuits and signal transduction.

How about the potential applications of the CNR1 receptor in drug development?

CNR1 receptors have potential applications in drug development. Some studies have shown that CNR1 receptor agonists or antagonists can be used to treat neurological disorders such as pain, depression, and anxiety.

Does the CNR1 gene polymorphism affect individual differences?

Polymorphisms in the CNR1 gene may cause differences in individual responses to medications. Some polymorphisms may increase an individual's sensitivity or tolerance to medications, which can affect the efficacy and safety of medications.

Do environmental factors influence CNR1 gene expression?

For example, some drugs, toxins, or stressors may affect the expression level of the CNR1 gene, thus affecting its function and signal transduction processes.