Recombinant Rhesus macaque IGFBP1 protein, His-tagged

• Cat.No.: IGFBP1-822R
• Product Overview: Recombinant Rhesus macaque IGFBP1 (Ala48-Asn281) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Insulin-like growth factor-binding protein 1 (IGFBP1) is also known as placental protein 12 (PP12), which contains oneIGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP1 can bindd both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of IGFBP1 can prolongd the half-life of the IGFs and alterd their interaction with cell surface receptors. Furthermore, IGFBP1 can promote cell migration. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: HEK293
• Species: Rhesus macaque
• Tag: His
• Predicted N Terminal: Ala48
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 27.2 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE).
• Protein length: Ala48-Asn281
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >98% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IGFBP1
• Official Symbol: IGFBP1
• Synonyms: AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
• Gene ID: 696994
• mRNA Refseq: XM_001085935.4
• Protein Refseq: XP_001085935.2
• UniProt ID: A0A1D5QTL3