Recombinant Rhesus monkey ABCC5 Protein, His-tagged
Cat.No. : | ABCC5-181R |
Product Overview : | Recombinant Rhesus monkey ABCC5 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Rhesus monkey |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | ABCC5 |
Synonyms : | ABCC5; multidrug resistance-associated protein 5; |
Gene ID : | 704326 |
mRNA Refseq : | NM_001260653 |
Protein Refseq : | NP_001247582 |
MIM : | |
UniProt ID : | H9FND4 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (16)
Ask a questionProgesterone, testosterone and their analogues
No clear research results. But the down-regulation of ABCC5 expression could significantly reduce the resistance of sorafenib to HCC cells.
The expression levels of ABCC2, ABCC4, ABCC5, and ABCG2 significantly increased in the pan-resistant cell line, and the ABCC5 level in the MCF-7-ADR cell line was 5.21 times higher than that in the control group.
MRP4 (ABCC4) and MRP5 (ABCC5) are organic anion transporters.
PLEKHA7, ABCC5, and KALRN have been identified as susceptible genetic markers related to glaucoma.
There is no clear result now. Some research show that ABCC5 was differently expressed and strongly related to the pathological stage of LIHC.
Not in all the tumors. Small molecular inhibitors of FOXM1 or ABCC5 have the potential to overcome paclitaxel chemoresistance in nasopharyngeal carcinoma patients
The role of ABCC5 in diabetes and obesity is unknown. ABCC5 protein expression levels are inversely related to fat mass and appear to play a role in the regulation of GLP-1 secretion from enteroendocrine cells.
No result shows that ABCC5 mutation will lead to diabetes. Research shows that ABCC5 transporter is a new type 2 diabetes susceptibility gene
Some study demonstrated that ABCC5 knockdown significantly inhibits PCa cell proliferation, migration, and invasion in vitro and suppresses tumor growth and metastasis in vivo.
It has not yet been reported.
There are many polymorphisms on ABCC5, such as, ABCC5 g.+7161G>A (rs1533682),g.+7161AA,g.+7161GG,g.-1679T>A, c.2T>C, c.343A>G, and c.1573G>A.
More research data are needed to prove.A study shows that the expression of ABCC5 was up-regulated in HCC and was associated with poor prognosis.
The protein is widely expressed in various tissues, with particularly high levels observed in the liver, kidney, and prostate.
Yes, please contact us for more information.
In adults, zebrafish abcc5 is extensively expressed, at higher levels in testis, brain, eye, ovary, intestine and kidney, but at relatively lower levels in gill, liver, heart and muscle.
Customer Reviews (3)
Write a reviewReasonable price and high quality
It is cost-effective to buy when promoting
There are many expression systems to choose from
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