Recombinant Zebrafish ADH8A

• Cat.No.: ADH8A-266Z
• Product Overview: Recombinant Zebrafish ADH8A full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: adh8a alcohol dehydrogenase 8a [ Danio rerio (zebrafish) ]
• Official Symbol: ADH8A
• Gene ID: 322482
• mRNA Refseq: NM_001001946
• Protein Refseq: NP_001001946
• UniProt ID: Q6P0S5

Reviews

09/04/2021

Shows exceptional selectivity in targeting specific cellular compartments in subcellular localization studies.

06/11/2021

Displays remarkable catalytic efficiency in glycosylation reactions.

Q&As

Are there any specific regulators or signaling pathways that control ADH8A expression and activity?

ADH8A expression and activity are regulated by specific regulators and signaling pathways, providing insights into the control of its expression.

Are there any genetic variations or polymorphisms in the ADH8A gene associated with altered alcohol metabolism or susceptibility to alcohol-related disorders?

Genetic variations or polymorphisms in the ADH8A gene may influence alcohol metabolism and susceptibility to alcohol-related disorders, highlighting the genetic component in its function.

Are there any interacting partners or cofactors that modulate ADH8A activity, and what are the underlying molecular mechanisms?

ADH8A can interact with specific partners or cofactors that modulate its activity, and studying the underlying molecular mechanisms provides insights into its regulation.

What is the impact of ADH8A deficiency or overexpression on alcohol metabolism and its physiological consequences?

Exploring the consequences of ADH8A deficiency or overexpression provides insights into its role in alcohol metabolism and its impact on physiological processes related to alcohol-related disorders.

How does ADH8A expression and activity change in response to alcohol exposure, and what are the molecular mechanisms involved?

ADH8A expression and activity can be influenced by alcohol exposure, and understanding the molecular mechanisms involved enhances our understanding of alcohol-related effects.

Can ADH8A metabolize other endogenous compounds or xenobiotics, and if so, what are their physiological implications?

ADH8A may have the ability to metabolize other endogenous compounds or xenobiotics, suggesting broader physiological implications beyond alcohol metabolism.

What is the tissue-specific expression pattern of ADH8A, and how does it differ from other ADH isoforms?

ADH8A exhibits a specific tissue expression pattern, distinguishing it from other ADH isoforms and suggesting its unique role in those tissues.

Can ADH8A be targeted by pharmacological agents or environmental factors to modulate its activity, and are there therapeutic implications?

Modulating ADH8A activity through pharmacological agents or environmental factors may have potential therapeutic implications, highlighting its targetability.

What is the three-dimensional structure of ADH8A, and how does it correlate with its catalytic activity and binding properties?

Investigating the three-dimensional structure of ADH8A provides valuable information on its catalytic activity and binding properties, aiding in understanding its function.

What are the enzymatic properties and substrate specificity of ADH8A, and how do they contribute to its function in alcohol metabolism?

The enzymatic properties and substrate specificity of ADH8A contribute to its function in alcohol metabolism, enabling efficient conversion of specific alcohol substrates.