Recombinant Zebrafish ADRA1BB

• Cat.No.: ADRA1BB-1746Z
• Product Overview: Recombinant Zebrafish ADRA1BB full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: adra1bb adrenoceptor alpha 1Bb [ Danio rerio (zebrafish) ]
• Official Symbol: ADRA1BB
• Gene ID: 492486
• mRNA Refseq: NM_001007358
• Protein Refseq: NP_001007359
• UniProt ID: Q5U3D9

Reviews

11/02/2020

The purity and activity of the protein are excellent, and I have observed reproducible results in my assays.

06/02/2019

the technical support from the manufacturer has been outstanding, with prompt and effective solutions provided to any issues that have arisen during my experiments.

08/16/2017

I am confident in the reliability of this protein and would highly recommend it to fellow researchers.

10/21/2016

I am pleased to report that the ADRA1BB protein provided by the manufacturer is of exceptional quality and meets all of my experimental requirements.

Q&As

How do ADRA1BB proteins interact with other medications?

ADRA1BB proteins can interact with other medications, particularly those that affect blood pressure or heart function. Patients should always inform their healthcare provider of any medications they are taking, including supplements and over-the-counter drugs.

Why is careful monitoring necessary for patients taking drugs that target ADRA1BB proteins?

Drugs that target ADRA1BB proteins can have a wide range of potential side effects, depending on the specific drug and dosage. It is important to carefully monitor patients who are taking these drugs to ensure that any side effects are promptly identified and managed.

How should ADRA1BB drugs be stored?

ADRA1BB drugs should be stored at room temperature, away from heat and sunlight. They should be kept in their original packaging and out of reach of children and pets. Unused medications should be properly disposed of according to local regulations.

Are there any side effects associated with ADRA1BB drugs?

As with any medication, ADRA1BB drugs can cause side effects. Common side effects include changes in blood pressure, heart rate, and mood. Other side effects may include headache, dizziness, and gastrointestinal disturbances.

Can ADRA1BB drugs be used to treat migraines?

While ADRA1BB proteins have been implicated in the regulation of pain and blood vessel constriction, drugs that specifically target these proteins are not currently approved for the treatment of migraines. However, some ADRA1BB agonists have been investigated as potential therapies for chronic pain conditions.

Can ADRA1BB drugs be used to treat anxiety or depression?

While ADRA1BB proteins have been implicated in the regulation of mood and anxiety, drugs that specifically target these proteins are not currently approved for the treatment of these conditions. However, some ADRA1BB agonists have shown promise as adjunct therapies for individuals with treatment-resistant depression.

Are there any genetic factors that can impact ADRA1BB function?

Yes, genetic variations can impact ADRA1BB function and influence a person's response to medications that target these proteins. Genetic testing may be helpful in identifying individuals who are more likely to experience adverse effects from ADRA1BB drugs.

Are ADRA1BB drugs addictive?

ADRA1BB drugs are not typically considered addictive, but some individuals may develop a dependence on them if taken at high doses or over a prolonged period of time.

What research is currently being conducted on ADRA1BB proteins?

Researchers continue to explore the role of ADRA1BB proteins in various medical conditions and their potential as therapeutic targets. Recent studies have focused on the potential use of ADRA1BB agonists for the treatment of chronic pain and as an adjunct therapy for certain types of cancer.

How do ADRA1BB proteins impact blood pressure?

ADRA1BB proteins are involved in the regulation of blood pressure by constricting blood vessels and increasing heart rate. Drugs that target ADRA1BB receptors can be used to treat hypertension and other cardiovascular conditions that are characterized by elevated blood pressure.

How are ADRA1BB drugs administered?

ADRA1BB drugs can be taken orally as tablets or capsules. In some cases, they may be administered as injections or IV infusions in a medical setting.

Can ADRA1BB drugs be used during pregnancy or breastfeeding?

The use of ADRA1BB drugs during pregnancy or breastfeeding is not recommended. These medications can cross the placenta and are excreted in breast milk, which can have potential risks for the developing fetus or infant.

How can drugs that target ADRA1BB proteins impact mental health?

Activation of ADRA1BB receptors can lead to increased arousal, vigilance, and anxiety, as well as improvements in attention and memory. In some cases, chronic activation of these receptors can lead to long-term negative effects on mental health, including anxiety disorders.

Can lifestyle changes such as exercise and diet impact ADRA1BB function?

Lifestyle changes such as exercise and diet can impact ADRA1BB function. Regular exercise can enhance the function of the cardiovascular and sympathetic nervous systems, while a healthy diet can support overall cardiovascular health.

What are some potential side effects of ADRA1BB antagonists?

ADRA1BB antagonists can be used to treat hypertension, as well as certain types of migraines and anxiety disorders. Some potential side effects include hypotension, dizziness, and fatigue.

What are some medical conditions that can be treated with ADRA1BB agonists?

ADRA1BB agonists can be used to treat conditions such as hypertension, heart failure, and shock by increasing cardiac output and causing vasoconstriction.

How do ADRA1BB proteins impact metabolism?

ADRA1BB proteins are involved in the regulation of metabolism, including the breakdown of fats and the release of glucose from liver cells. Drugs that target ADRA1BB receptors can be used to treat conditions such as metabolic syndrome and type 2 diabetes.

Can ADRA1BB drugs be safely used during pregnancy and breastfeeding?

The safety of ADRA1BB drugs during pregnancy and breastfeeding has not been well established. It is important for pregnant or breastfeeding women to consult with a healthcare provider before taking any medications that target ADRA1BB proteins.

Can ADRA1BB drugs be used to treat ADHD?

While ADRA1BB proteins have been implicated in the regulation of attention and focus, drugs that specifically target these proteins are not currently approved for the treatment of ADHD. However, some ADRA1BB agonists have been investigated as potential treatments for other cognitive disorders, such as Alzheimer's disease.