Recombinant Zebrafish ANGPTL1B

• Cat.No.: ANGPTL1B-7896Z
• Product Overview: Recombinant Zebrafish ANGPTL1B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: angptl1b angiopoietin-like 1b [ Danio rerio (zebrafish) ]
• Official Symbol: ANGPTL1B
• Gene ID: 334311
• mRNA Refseq: NM_001199970
• Protein Refseq: NP_001186899
• UniProt ID: Q7SXV7

Reviews

11/25/2022

They continuously invest in research and development, ensuring that their offerings remain at the forefront of scientific advancements.

01/29/2020

With the ANGPTL1B protein and the manufacturer's assistance, my trials have been empowered to yield impactful findings, contributing to advancements in the field of biomedical research.

08/14/2019

The protein's unique properties allow researchers to gain insights into the underlying mechanisms and explore potential therapeutic interventions.

12/27/2016

Whether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.

Q&As

Are there any known interacting partners or receptors of ANGPTL1B protein?

The specific interacting partners or receptors of ANGPTL1B protein have not been extensively characterized. However, some members of the angiopoietin-like protein family, such as ANGPTL3 and ANGPTL4, have been shown to interact with receptors like integrins and lipoprotein receptors. Further research is needed to identify potential interacting partners of ANGPTL1B.

Is ANGPTL1B protein associated with any diseases or conditions?

Limited studies have linked ANGPTL1B protein with certain diseases or conditions. One study found that ANGPTL1B expression is significantly increased in the adipose tissue of obese individuals, suggesting its potential involvement in obesity and metabolic disorders. Another study suggested a potential correlation between ANGPTL1B levels and breast cancer progression. However, more research is needed to establish a clear association between ANGPTL1B protein and specific diseases or conditions.

Is ANGPTL1B protein expressed in specific tissues?

ANGPTL1B protein expression appears to be primarily confined to specific tissues. Studies have shown its expression in adipose tissue, liver, and skeletal muscle, suggesting its role in metabolic regulation. However, further research is required to determine if there are any additional tissues where ANGPTL1B protein is expressed.

Are there any drugs or therapies targeting ANGPTL1B protein?

As of now, there are no specific drugs or therapies targeting ANGPTL1B protein. However, the potential therapeutic implications of ANGPTL1B in regulating angiogenesis and metabolism suggest that targeting this protein could have therapeutic potential in the future. Further research is needed to identify specific drug targets and develop targeted therapies.

What are the potential therapeutic implications of studying ANGPTL1B protein?

Studying the role of ANGPTL1B protein has the potential to provide insights into mechanisms related to angiogenesis, metabolism regulation, and lipid metabolism disorders. Understanding its function and potential therapeutic implications could lead to the development of targeted therapies for angiogenesis-related diseases, obesity, and metabolic disorders.

What are the known signaling pathways or mechanisms involving ANGPTL1B protein?

The signaling pathways and mechanisms involving ANGPTL1B protein have not been extensively studied. However, it has been proposed that ANGPTL1B may interact with integrins and modulate the phosphorylation of downstream signaling molecules involved in angiogenesis.

What diseases or conditions are associated with ANGPTL1B protein?

The exact role of ANGPTL1B protein in diseases or conditions is still being investigated. However, some research suggests its potential involvement in angiogenesis-related disorders, obesity, and lipid metabolism disorders. Further studies are needed to establish definitive associations.

What are the potential functions of ANGPTL1B protein?

The exact functions of ANGPTL1B protein are not fully understood yet, but research suggests it may play a role in regulating angiogenesis, lipid metabolism, and energy homeostasis. It has been proposed that ANGPTL1B inhibits angiogenesis, the formation of new blood vessels, by interfering with the signaling pathway involved in blood vessel growth. Additionally, ANGPTL1B has been shown to regulate lipoprotein metabolism and triglyceride levels, suggesting its involvement in lipid metabolism. Further studies are needed to fully elucidate the functions of ANGPTL1B protein.

Can ANGPTL1B protein be used as a diagnostic or prognostic marker?

Currently, there is not enough evidence to support the use of ANGPTL1B protein as a diagnostic or prognostic marker for any disease or condition. While some studies have shown correlations between ANGPTL1B expression and certain conditions, more research is needed to validate its utility as a diagnostic or prognostic marker. Additionally, factors such as interindividual variation and other confounding variables need to be considered in future studies.

Are there any known mutations or genetic variations in the ANGPTL1B gene?

Genetic variations and mutations affecting the ANGPTL1B gene have not been extensively studied thus far. It is possible that there may be certain genetic variations or mutations, but more research is needed to fully understand their impact on protein function and association with diseases or conditions.

Are there any clinical trials targeting ANGPTL1B protein?

As of my current knowledge, there are no ongoing clinical trials specifically targeting ANGPTL1B protein. However, please note that clinical trials are continuously evolving, so it's important to refer to resources like clinical trial registries or scientific literature for the most up-to-date information.

Can ANGPTL1B protein be used as a therapeutic target?

The therapeutic potential of targeting ANGPTL1B protein is yet to be established. More research is required to fully understand its function and determine if it can serve as an effective target for therapeutic interventions in various diseases or conditions.