Recombinant Zebrafish APODB

• Cat.No.: APODB-3588Z
• Product Overview: Recombinant Zebrafish APODB full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: apodb apolipoprotein Db [ Danio rerio (zebrafish) ]
• Official Symbol: APODB
• Gene ID: 567972
• mRNA Refseq: NM_001037695
• Protein Refseq: NP_001032784
• UniProt ID: Q3B7Q5

Reviews

11/24/2020

Their collaboration during trial design and data analysis enhances the reliability and significance of my research findings.

08/14/2019

the APODB protein's exceptional quality, coupled with the manufacturer's outstanding technical support, ensures that it fulfills my experimental needs with utmost precision and efficacy.

02/07/2018

the APODB protein is an exceptional tool for investigating the intricate mechanisms and pathogenesis of amyloid-related diseases.

07/06/2017

Their profound knowledge and expertise will undoubtedly help me overcome any challenges that arise, and their prompt assistance ensures a seamless progression of my research.

Q&As

Where is APODB protein found in the body?

APODB protein is found in various tissues and fluids, including plasma, cerebrospinal fluid, tears, breast milk, and brain tissue.

Are there any genetic mutations associated with APODB protein?

Genetic variations in the APODB gene have been identified, including single nucleotide polymorphisms (SNPs). Some of these SNPs have been associated with altered protein levels or increased susceptibility to certain diseases. However, their functional significance and clinical implications are still being investigated.

Are there any diseases or disorders associated with APODB protein?

APODB protein has been implicated in various conditions, including cancer, neurodegenerative diseases, metabolic disorders, and inflammatory conditions. However, the exact mechanisms and roles in these diseases are still being investigated.

What are the potential neurological functions of APODB protein?

APODB protein is highly expressed in the brain and appears to play a neuroprotective role. It has been associated with neuronal survival, axon growth, and protection against neurodegenerative diseases such as Alzheimer's and Parkinson's.

Is there any known association between APODB protein and inflammation?

APODB protein has been implicated in inflammatory conditions like rheumatoid arthritis and atherosclerosis. It may modulate inflammation by interacting with immune cells and influencing the release of inflammatory mediators.

How is APODB protein involved in cancer?

APODB protein has been found to be upregulated in certain types of cancer, including breast, ovarian, and colorectal cancer. It is believed to promote cancer cell survival and growth and may play a role in tumor progression and metastasis.

Can APODB protein be used as a biomarker for certain diseases?

APODB protein levels have been found to be altered in certain diseases and conditions, making it a potential biomarker for diagnostic or prognostic purposes. However, more research is needed to establish its clinical utility.

Can APODB protein be used as a therapeutic target for metabolic disorders?

As APODB protein is involved in lipid metabolism and metabolic regulation, it is a potential target for the treatment of metabolic disorders. Modulating its activity may have implications for improving metabolic health, but more research is needed to explore this possibility.

How is APODB protein detection and analysis typically conducted?

APODB protein detection and analysis can be performed using various techniques, including immunological methods like ELISA or Western blotting. Additionally, gene expression analysis and proteomic studies help in understanding its expression patterns and functional implications in different contexts.

How is APODB protein involved in metabolic disorders?

APODB protein has been linked to metabolic disorders such as obesity, type 2 diabetes, and dyslipidemia. It may influence lipid metabolism, insulin sensitivity, and adipocyte function, contributing to the development of these conditions.

Does APODB protein have any role in neurodegenerative diseases?

APODB protein has been implicated in neurodegenerative diseases like Alzheimer's and Parkinson's. It is thought to have protective effects against neurodegeneration and may play a role in mitigating the damage caused by protein misfolding and oxidative stress.

Can APODB protein be used as a target for cancer therapy?

Targeting APODB protein is being explored as a potential therapeutic strategy for cancer. Inhibiting its activity or expression may disrupt cancer cell survival and growth. However, more research is needed to determine the feasibility and effectiveness of this approach.

Does APODB protein have any role in aging?

APODB protein has been investigated for its potential involvement in the aging process. It has been suggested that APODB may contribute to the maintenance of cellular homeostasis and protection against age-related damage. However, more research is needed to establish its precise role in aging.

Are there any known therapeutic implications of targeting APODB protein?

Due to its involvement in various disease processes, APODB protein is being explored as a potential therapeutic target. Modulating its levels or activity may have implications for conditions such as cancer, neurodegenerative diseases, and metabolic disorders. However, specific therapeutic approaches are still in the experimental stages.

How does APODB protein contribute to stress response?

APODB protein has been shown to be induced in response to various stressors, such as oxidative stress, heat shock, and neurodegenerative insults. It is believed to have protective effects by modulating cell signaling pathways and promoting cell survival.

How is APODB protein regulated in the body?

The expression and activity of APODB protein are regulated by various factors, including hormones, transcription factors, and cellular signaling pathways. Research is ongoing to further understand the precise regulatory mechanisms.

Are there any known interactions or binding partners of APODB protein?

APODB protein has been reported to interact with several molecules and proteins, including lipids, cell surface receptors, and other signaling proteins. These interactions contribute to its diverse functions and regulatory mechanisms.