Recombinant Zebrafish ASAH1A

• Cat.No.: ASAH1A-1595Z
• Product Overview: Recombinant Zebrafish ASAH1A full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: asah1a N-acylsphingosine amidohydrolase (acid ceramidase) 1a [ Danio rerio (zebrafish) ]
• Official Symbol: ASAH1A
• Gene ID: 450068
• mRNA Refseq: NM_001006088
• Protein Refseq: NP_001006088
• UniProt ID: Q5XJR7

Reviews

10/25/2019

I greatly appreciate their commitment to ensuring my research is a success.

05/07/2017

The ASAH1A Protein offers a wide range of applications, making it highly versatile for various experimental settings.

09/19/2016

Its purity and consistency are of the highest standards, allowing for precise and reliable results in my research endeavors.

Q&As

How does ASAH1A protein dysfunction contribute to SMA-PME?

ASAH1A protein dysfunction in SMA-PME leads to the accumulation of ceramide in nerve cells, causing neurodegeneration and the characteristic symptoms of the condition.

What happens if there is a deficiency in ASAH1A protein?

Deficiency of ASAH1A protein leads to the accumulation of ceramide, which can result in various health conditions, including Farber disease.

Besides Farber disease, are there any other disorders associated with ASAH1A protein dysfunction?

Apart from Farber disease, ASAH1A protein dysfunction has also been implicated in spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME), which is a rare neurological disorder.

How does ASAH1A protein contribute to lipid metabolism?

ASAH1A protein hydrolyzes ceramide into sphingosine and fatty acids, thus participating in the degradation pathway of ceramide metabolism.