Recombinant Zebrafish ATP2A2B
Cat.No. : | ATP2A2B-3354Z |
Product Overview : | Recombinant Zebrafish ATP2A2B full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | atp2a2b ATPase, Ca++ transporting, cardiac muscle, slow twitch 2b [ Danio rerio (zebrafish) ] |
Official Symbol : | ATP2A2B |
Gene ID : | 568265 |
mRNA Refseq : | NM_001030277 |
Protein Refseq : | NP_001025448 |
UniProt ID : | Q6ZM60 |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe ATP2A2B protein contains multiple domains, including an N-terminal domain and a C-terminal domain. Its C-terminal domain contains an ATP-binding site and a calcium-binding site for ATP hydrolysis and calcium transport.
Researchers can use cell culture models and animal models to study the function of ATP2A2B by overexpressing, knocking down or mutating the gene. In addition, biochemical and molecular biological techniques, such as co-immunoprecipitation and calcium imaging, can be used to explore the interaction and functional regulation mechanism between ATP2A2B and other proteins.
Mutations in ATP2A2B protein are associated with muscle diseases, including muscular dystrophy and X-linked muscular relaxation. These mutations may lead to abnormal function of ATP2A2B protein and affect calcium transport and regulation.
The protein regulates the calcium concentration of muscle cells by transporting intracellular calcium ions to the sarcoplasmic reticulum. This Ca 2 + transport process is a key step in muscle contraction and relaxation and is essential for maintaining muscle function and motor regulation.
ATP2A2B protein is a calcium transporter located in the sarcoplasmic reticulum (sarcoplasmic reticulum), which is responsible for transporting intracellular calcium ions from the cytoplasm to the sarcoplasmic reticulum. This process is essential for muscle contraction and relaxation.
The expression and activity of ATP2A2B protein are affected by a variety of regulatory mechanisms, including transcriptional regulation, post-translational modification, and protein-protein interactions. These mechanisms can regulate the abundance and function of ATP2A2B protein in cells.
Customer Reviews (3)
Write a reviewUsing ATP2A2B significantly improved the efficiency of my experiments and reduced unnecessary waste of time.
The catalytic activity of ATP2A2B is amazing, and its ability to achieve efficient catalysis under mild conditions is appreciated for its mild nature.
They produce ATP2A2B that are stable and have no problems with long-term storage.
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