Recombinant Zebrafish CADM2B

• Cat.No.: CADM2B-6317Z
• Product Overview: Recombinant Zebrafish CADM2B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: cadm2b cell adhesion molecule 2b [ Danio rerio (zebrafish) ]
• Official Symbol: CADM2B
• Gene ID: 571698
• mRNA Refseq: NM_001113555
• Protein Refseq: NP_001107027
• UniProt ID: B0F6R2

Reviews

02/18/2022

Highly recommend.

07/14/2019

I've been recommending the product to all my friends.

10/03/2018

I've tried various products in the past, but this one stands out.

Q&As

What is the potential role of CADM2b in grass carp, particularly in relation to immune function?

CADM2b gene in grass carp may mediate the adhesion of different cells in various tissues and organs. Since CADM2b protein is primarily expressed and secreted by non-immune cells, it may play a role in non-specific defense against infectious diseases by mediating the adhesion between immune macrophages and pathogenic target cells.

What important insights do the results of this study provide regarding the cadm2b gene in grass carp and zebrafish?

The results of this study indicate that the expression of the cadm2b gene varies among different adult tissues, with higher expression observed in the brain and some other tissues. This helps further research into the function of the cadm2b gene and its association with specific tissues or physiological processes.

Why did the researchers design specific primers based on the intron structure data of the zebrafish CADM2B gene?

The researchers designed specific primers based on the intron structure data of the zebrafish cadm2b gene to perform PCR amplification and study the expression of the cadm2b gene in grass carp. This helps determine the similarity and genomic structure of the cadm2b gene between grass carp and zebrafish.

In which adult grass carp tissues was the expression of cadm2b detected?

Semi-quantitative RT-PCR results showed that the cadm2b gene was only detected in the brain of adult grass carp. However, using nested PCR primers, the researchers also detected cadm2b expression in the liver, kidney, heart, and muscle tissues. Expression was still not detected in the gill and pancreas tissues.

What similarities are mentioned between the CADM2b discussed in this study and CADM2b in mice, and what might this similarity imply?

The tissue expression pattern of CADM2b in adult grass carp is similar to that in adult mice. This suggests that the function of the CADM2b gene and its tissue-specific transcriptional regulation mechanisms are conserved in vertebrate evolution, potentially performing similar biological functions.