Recombinant Zebrafish INSL5B

• Cat.No.: INSL5B-6935Z
• Product Overview: Recombinant Zebrafish INSL5B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: insl5b insulin-like 5b [ Danio rerio (zebrafish) ]
• Official Symbol: INSL5B
• Gene ID: 100008569
• mRNA Refseq: NM_001128556
• Protein Refseq: NP_001122028
• UniProt ID: A0ZYT5

Reviews

07/20/2021

The product's versatility allowed us to apply it to a wide range of experimental techniques and research areas.

07/27/2020

The product's customizability allowed us to fine-tune experiments to match our specific research objectives.

09/21/2016

We appreciated the product's recognition in peer-reviewed journals, further establishing its importance in our field.

Q&As

Which organism's genome experienced an expansion of RLN genes due to WGD, and how many RLN genes are present in its genome?

The organism with an expansion of RLN genes due to WGD is Danio rerio (zebrafish), and it has six RLN genes, including two paralogs each for rln3 and insl5 genes.

What is the INSL5B protein, and what gene encodes it?

The INSL5B protein is a member of the relaxin (RLN) and insulin (INSL)-like peptides, and it is encoded by the insl5b gene.

How does the INSL5B gene relate to the relaxin (RLN) and insulin (INSL)-like peptides in the INSL/RLN superfamily?

The INSL5B gene is part of the INSL/RLN superfamily, which includes seven genes in humans activating the G-protein coupled receptor RXFP 1-4.

How many rounds of whole genome duplication (WGD) influenced the evolution of RLN genes in early vertebrate evolution?

Two rounds of whole genome duplication (WGD) in early vertebrate evolution and an additional WGD in the teleost lineage influenced the evolution of RLN genes.

What is the significance of the expression of insl5a and insl5b in D. rerio embryonic development?

The expression of insl5a and insl5b in D. rerio embryonic development is reported for the first time, with both paralogs present in all analyzed embryonic stages.

In which tissues or cells are insl5a and insl5b expressed during embryonic development?

During embryonic development, insl5a shows a restricted signal in intestinal cells and the pancreatic region at 72 hpf, while at 96 hpf, both insl5a and insl5b are expressed in specific intestinal cells.

What are the paralogs of the rln3 gene and insl5 gene in Danio rerio?

The paralogs for the rln3 gene are rln3a and rln3b, and for the insl5 gene, they are insl5a and insl5b.