Recombinant Zebrafish RB1

• Cat.No.: RB1-4856Z
• Product Overview: Recombinant Zebrafish RB1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: rb1 retinoblastoma 1 [ Danio rerio (zebrafish) ]
• Official Symbol: RB1
• Gene ID: 777733
• mRNA Refseq: NM_001077780
• Protein Refseq: NP_001071248
• UniProt ID: A0JMQ4

Reviews

07/15/2022

Efficient protein purification, delivers consistent yield and purity.

01/19/2021

Expertise in protein engineering, a trusted resource for research.

10/09/2019

Reliable protein crystallization services, exceptional results achieved.

Q&As

What is the impact of RB1 mutations on the development of retinoblastoma and other cancers?

Mutations in RB1 lead to retinoblastoma and increase the risk of other cancers, disrupting normal cell cycle control.

How does RB1 interact with transcription factors and affect gene expression?

RB1 interacts with transcription factors to regulate gene expression, impacting various cellular processes.

What role does RB1 play in DNA damage response and repair mechanisms?

RB1 plays a crucial role in the DNA damage response, facilitating repair and maintaining genomic stability.

How does RB1 regulate the cell cycle, particularly the transition from G1 to S phase?

RB1 controls the G1 to S phase transition in the cell cycle, preventing unregulated cell division.

How do alterations in RB1 expression or function influence stem cell differentiation and tissue regeneration?

Changes in RB1 function affect stem cell differentiation and tissue regeneration, influencing tissue maintenance and repair.

What are the mechanisms by which RB1 modulates cellular senescence and apoptosis?

RB1 influences cellular senescence and apoptosis, playing a role in aging and cell turnover.

How does RB1 contribute to tumor suppression and the prevention of uncontrolled cell proliferation?

As a tumor suppressor, RB1 prevents excessive cell proliferation and contributes to cancer prevention.