Recombinant Zebrafish RNF168

• Cat.No.: RNF168-10228Z
• Product Overview: Recombinant Zebrafish RNF168 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: rnf168 ring finger protein 168 [ Danio rerio (zebrafish) ]
• Official Symbol: RNF168
• Gene ID: 334081
• mRNA Refseq: NM_199855
• Protein Refseq: NP_956149
• UniProt ID: Q7T308

Reviews

10/04/2020

Not only does it provide reliable and consistent results due to its high quality and purity, but it also holds significant value in understanding cellular processes and disease mechanisms.

09/03/2017

This commitment to excellence ensures that researchers are provided with the most advanced and reliable tools for their investigations.

06/19/2017

the RNF168 protein offers numerous advantages in trials and research experiments.

Q&As

Are there any current clinical trials involving RNF168 protein?

Clinical trials investigating the potential use of RNF168 as a target for cancer therapy or as a biomarker for cancer prognosis may be underway, but specific details would need to be checked.

How does RNF168 protein contribute to the DNA damage response?

RNF168 plays a role in initiating a signaling cascade that leads to the recruitment of other DNA repair proteins to the site of DNA damage, promoting repair and maintaining genomic stability.

How does RNF168 protein interact with other proteins in the DNA repair pathway?

RNF168 interacts with various proteins involved in the DNA damage response, such as 53BP1 and BRCA1, to coordinate the repair of DNA lesions and maintain genomic stability.

Can mutations in the RNF168 gene be inherited and lead to an increased risk of cancer?

Yes, inherited mutations in the RNF168 gene can increase the risk of developing certain cancers, particularly those associated with DNA damage and repair deficiencies.

Are there any known side effects or toxicities associated with modulating RNF168 activity in cancer therapy?

The potential side effects and toxicities of targeting RNF168 in cancer therapy are still being explored, and would depend on the specific approach and modality used.